Some isothiazolines
(Rev. 2007)
1,2-Benzisothiazoline-3-one
| 5-chloro-2-methylisotiazoline-3-one
2-Methyl-4-isotiazoline-3-one |
Octylisotiazoline-3-one
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1,2-BENZISOTHIAZOLINE-3-ONE
CAS No
2634-33-5
Synonyms
BIT
1,2-Benzisothiazolinone
Physical data
Melting point:
152°C
Boiling point: -
Vapour pressure:
-
Water solubility: 1 g/l
5-CHLORO-2-
METHYLISOTHIAZOLINE-3-ONE
CAS No 26172-55-4
Synonyms
MIT
5-chloro-2-methyl-3-isothiazolone
Physical data
Melting point:
52-55 °C
Boiling point: -
Vapour pressure:
0.025* kPa
Water solubility:
can be mixed
2-METHYL-4-ISOTHIAZOLINE-3-ONE
CAS no 2682-20-4
Synonyms
2-Methyl-3-isothiazolone
Physical data
Melting point: 47-50°C
Boiling point: 93°C
Vapour pressure: 0.025* kPa
Water solubility: can be mixed
OCTYLISOTHIAZOLINE-3-ONE
CAS No 26530-20-1
Synonyms
Octhilinone
Physical data
Melting point: -
Boiling point: 120°C
Vapour pressure: -
Water solubility: 0.5 g/l
*
Vapour pressure refers to Kathon
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Isothiazolines are used as
preservatives in the paint industry, where they serve to protect the product from fungal and mould attacks. One of the more common products of this kind
used to be Kathon®, a 1.5%-aqueous solution consisting of 1 part
methylisothiazolinone (CAS No 2682-20-4), and 3 parts of
chloromethylisothiazolinone (CAS No 26172-55-4). This mixture can also be
identified with a specific CAS No, 55965-84-9. To avoid risk of allergy the
much weaker 1,2-benzisothiazolinone (commonly called BIT) is used. This is above all used as a preservative in latex
paints.

These substances are used in paint, adhesives, jointing compounds, cutting fluids and detergents. Paint, adhesive and detergents are products sold for both professional and
consumer use.
Octylisothiazolinone is also used almost exclusively as a preservative in latex paints, but a small proportion is also used as a preservative in the leather and fur
industries.
Isothiazolines are also used as slime control agents in the pulp industry and as wood impregnating agents.
Low concentrations, mostly <<0.01 %, of isothiazolines are present in a large number of products, which means that the volumes reported are averages with a wide
interval.
Concentrations are often given as maximum values, which compounds the uncertainty regarding these
volumes.

These substances are not manufactured in Sweden but are imported, either as raw materials or as components of chemical
products.
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